Association of Crohn’s Disease and Celiac Disease: Causal link or only coincidence?

  • Tolga Duzenli Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Mustafa Kaplan Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Alpaslan Tanoglu Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Demet Altun Department of Pediatrics, Etimesgut Military Hospital, Etimesgut, Ankara
  • Hakan Cermik Department of Pathology, Etimesgut Military Hospital, Etimesgut, Ankara, Turkey
Keywords: Crohn’s Disease, Celiac Disease

Abstract

Crohn’s disease (CD) is a chronic inflammatory bowel disease that affects any part of the gastrointestinal tract, most commonly terminal ileum and proximal colon; and Celiac Disease (CeD) is immuno-mediated systemic disease caused by gluten and similar prolamins in genetically susceptible individuals. Concomitant occurrence of CD and CeD is rare and there are limited literature data regarding the association of CeD to CD. Although, recent findings propose shared mechanisms, genetics and functional pathways. Herein, we report a case that has co-occurrence of CD and CeD and rewiew the literature of the association between these two diseases.

Author Biographies

Tolga Duzenli, Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Mustafa Kaplan, Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Alpaslan Tanoglu, Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Demet Altun, Department of Pediatrics, Etimesgut Military Hospital, Etimesgut, Ankara

Department of Pediatrics, Etimesgut Military Hospital, Etimesgut, Ankara

Hakan Cermik, Department of Pathology, Etimesgut Military Hospital, Etimesgut, Ankara, Turkey

Department of Pathology, Etimesgut Military Hospital, Etimesgut, Ankara, Turkey

Crohn’s Disease
Published
2016-12-31
How to Cite
Duzenli, T., Kaplan, M., Tanoglu, A., Altun, D., & Cermik, H. (2016). Association of Crohn’s Disease and Celiac Disease: Causal link or only coincidence?. Disease and Molecular Medicine, 4(4), 77-80. https://doi.org/10.5455/dmm.20161011084217
Section
Case Report

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