May Ultrasonography Diagnosed Hepatic Steatosis be Predictor of Metabolic Syndrome Among Aviators?

  • Alpaslan Tanoglu Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Mustafa Aparcı Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Gökçen Okur Aktaş Department of Radiology and Aviation Medicine, Etimesgut Military Hospital, Ankara, Turkey
  • Mehmet Karaduman Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey
  • Cengiz Ozturk Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey
  • Mustafa Kaplan Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
  • Sercan Okutucu Department of Cardiology, Etimesgut Military Hospital, Ankara, Turkey
Keywords: Aviator, cardiovascular risk factors, nonalcoholic fatty liver disease, metabolic syndrome

Abstract

Patients with nonalcoholic fatty liver disease (NAFLD) have higher cardiovascular morbidity and mortality rates compared with the general population. Because of several periodic examinations, in general, aviators are healthier than general population. We aimed to evaluate whether ultrasonography diagnosed hepatic steatosis (HS) may be a noninvasive predictor of metabolic syndrome (MetS) among aviators. About 32 aviators with NAFLD and 32 healthy aviators were included in the study. Age, body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP), laboratory parameters (fasting blood glucose [FBG], total cholesterol [TC], low‑density lipoprotein‑cholesterol [LDL‑C], and high‑density lipoprotein‑cholesterol [HDL‑C], very LDL‑C [VLDL‑C], triglyceride [TG]), TC/HDL‑C ratio were obtained from the medical history, physical examination and laboratory result chart of medical recordings. The prevalence of HS was %16.9 (n = 32) in the aviators who were performed abdominal ultrasonography as an annual routine test. BMI (26.1 ± 1.9 vs. 24.0 ± 1.9, P < 0.001), SBP (119.1 ± 11.2 vs. 110.7 ± 7.5, P = 0.001), and DBP (76.6 ± 7.6 vs. 70.1 ± 6.9, P = 0.001), FBG (97.7 ± 9.1 vs. 90.1 ± 13.3, P = 0.010), TC (219.9 ± 42.3 vs. 191.2 ± 30.1, P = 0.003), LDL‑C (140.2 ± 34.3 vs. 117.9 ± 22.2, P = 0.003) and VLDL‑C (32.1 ± 14.5 vs. 23.9 ± 12.5, P = 0.019), TC/HDL‑C ratio (4.5 ± 0.9 vs. 3.9 ± 0.8, P = 0.011) were significantly higher in aviators with HS compared to healthy ones. MetS (≥3 criteria) was significantly higher in aviators with HS compared to healthy ones (53.1% vs. 18.8%, P = 0.004). HS may be a reliable representative of MetS, which can
be non‑invasively screened among aviators. Moreover, HS may be a clinical indicator of MetS among aviators who need further cardiovascular evaluation and also counseling for lifestyle and dietary changes, and exercise activity programing.

Author Biographies

Alpaslan Tanoglu, Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Gastroenterology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Mustafa Aparcı, Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Gökçen Okur Aktaş, Department of Radiology and Aviation Medicine, Etimesgut Military Hospital, Ankara, Turkey

Department of Radiology and Aviation Medicine, Etimesgut Military Hospital, Ankara, Turkey

Mehmet Karaduman, Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey

Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey

Cengiz Ozturk, Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey

Department of Internal Medicine, Etimesgut Military Hospital, Ankara, Turkey

Mustafa Kaplan, Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Department of Cardiology, GATA Haydarpasa Training Hospital, Istanbul, Turkey

Sercan Okutucu, Department of Cardiology, Etimesgut Military Hospital, Ankara, Turkey

Department of Cardiology, Etimesgut Military Hospital, Ankara, Turkey

aviators with and without ultrasound-diagnosed nonalcoholic fatty liver disease
Published
2015-12-31
How to Cite
Tanoglu, A., Aparcı, M., Okur Aktaş, G., Karaduman, M., Ozturk, C., Kaplan, M., & Okutucu, S. (2015). May Ultrasonography Diagnosed Hepatic Steatosis be Predictor of Metabolic Syndrome Among Aviators?. Disease and Molecular Medicine, 3(4), 35-42. https://doi.org/10.5455/dmm.20160126121441
Section
Original Article

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