Cortisone Acetate Induced Acute Flare-Up of HBV Infection in a Growth Hormone Deficient Patient
Reactivation of hepatitis B virus is a known complication of immunosuppressive therapy and may cause liver failure and even death. A twenty-year-old male patient visited the endocrinology department because of short stature and diagnosed as growth hormone deficient. Somatropin and cortisone acetate were initiated. After six months, HBV reactivation was occurred. Antiviral treatment with lamivudine was initiated after the increase in transaminases. After a six months’ initiating lamivudine therapy, his physical examination and laboratory test results were found to be normal. In conclusion, every patient who are planned to be received immunosuppressive therapy should be screened for HBV infection.